罢丑别听University of Cambridge听丑补蝉听received听multi-million-pound funding from the government for a clinical trial of its COVID-19 vaccine.听
Trial preparations are underway for the vaccine, which will be delivered via an innovative needle-free injection technology听developed by US firm听PharmaJet.听
It is hoped that a successful trial will result in the widespread听availability of a low-cost vaccine.听听
The vaccine听has been听developed by听DIOSynVax, a spinoff company supported by the University of Cambridge, and听uses computer modelling of the virus鈥� structure to identify the distinct genetic code.听听
The combined artificial intelligence and synthetic biology approach allows for development of a vaccine that is specific to developing antibodies against the SARS-CoV-2 virus.听
鈥淥ur approach using synthetic DNA to deliver custom-designed, immune-selected vaccine antigens is revolutionary and is ideal for complex viruses such as coronavirus,鈥� said听Dr.听Jonathan Heeney, CEO of听DIOSynVax.听
鈥淚f successful, it will result in a vaccine that should be safe for widespread use that can be manufactured and distributed at low cost.鈥�听
罢丑别听PharmaJet听System was chosen due to its record of increasing the efficacy of nucleic acid-based vaccines and therapeutics.听
鈥淚t is especially exciting that the clinical trial will test giving the vaccine through people鈥檚 skin using a device without any needles as together with stable DNA vaccine technology,听this could be a major breakthrough in being able to give a future vaccine to huge numbers of people across the world,鈥澨�said听Professor Saul Faust, director of the National Institute for Health Research Southampton clinical research facility where the clinical trial will take place.听
Chris Cappello, president and CEO at听PharmaJet, added:听鈥淲e are pleased to be collaborating with the University of Cambridge and听DIOSynVax听as the delivery system for their vaccine against the SARS-CoV-2.听
鈥淥ur听needle-free听systems have been proven to improve the immune response for multiple RNA/DNA-based vaccines as well as being used to eradicate diseases such as influenza, measles and polio.鈥�