HealthTechInvestment

Thymiahasraised a £780,000pre-seed round to scale its platform to assess for and monitor depression.

Thetechnologyremoves subjectivity from mental health assessments: instead of answering questionnaires, patients play specially designed videogameswhich use cutting-edge Neuropsychology, Linguistics and Machine Learning to detect signs of depression, as well as monitor whether symptoms are improving or worsening over time.

Through its online platform,Thymiawill empower clinicians to makefaster and more accurate clinical decisions by making mental illness as objectively measurable as visible physical conditions.

KodoriAG and Calm/Storm co-led this round, which was also joined by FormVentures and included backing from Entrepreneur First.

Co-founded by neuroscientist Dr EmiliaMolimpakisand theoreticalphysicist Dr Stefano Goria,Thymiawas created after a close friend of Emilia’s developed depression.

“Thymiawas born when a close friend of mine tried to take her own life. Her friends anddoctors missed the signs that she was so seriously unwell, not least because the process of accessing the right treatment was based on out-dated methodologies not fit for the complexities and nuances of an illness like depression,” she said.

“Depression is a massive, constantly growing societal and economic problem; it is a leadingcause of disability and suicides and costs the UK economy billions annually in lost productivity.

“COVID-19 has further compounded the issue, unleashing a mental illness ‘tsunami’ due to a lack of in-person appointments, but also its harsh societal effects –social isolation, employment loss, bereavement and grief.

“Despite this, GPs and psychiatrists are using the same diagnostic questionnaires thathave been around since the 1960s. Rating how sad you feel on a scale of 0 to 3 simply is not enough to capture the subtle nuances of early signs of depression nor track the complexities of ongoing mental illness, but our clinicians have not been given a betteroption.”

Thymiaprovides them with a more accurate, faster process for assessing and monitoring major depression.

Emilia and Stefano, who is an expert in explainable, multi-modalAI, have carefully created video game-style activities and challenges for patients to interact with, such as verbally describing animated scenes or interacting with moving objects.

Whilst users complete the games, theThymiasoftware anonymously analysesvoice(both how someone speaks andwhat they are saying),video(micro-expressions andeye-gaze)andbehaviouralmeasures(reaction times and error rates).

The software then identifies data patterns indicative of depressionto help pinpoint a diagnosis more quickly and accurately.

Crucially, it will also show if any treatments–whethertherapies or medications–areworking.

Thymiais gathering rich data from hundreds of subjects with majordepressive disorder and a normative control group to ethically and inclusively train their AI.

Theysaystheyare removing the racial, gender and age biases typically associated with AI models to make their assessments as accurate and objective as possible.

They have already established collaborations and partnerships with several world-leading research institutes,including UCL and King’s College London, to help scale use of the technology to other cognitive disorders.

LucanusPolagnoli, Founder and Managing Partner at Calm/Storm,said:“We’re very excited aboutThymia. It’s going tobring the same level of objectivity to mental health that we expect in the realm of physical health.

“EmiliaandStefano impressed us from day one with their passion, academic prowess, and rigorous commitment to building a truly inclusive mental health tool.”